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Gastroenterology 1998
In humans, immunohistochemistry using a monoclonal antibody showed that the GLP-1 receptor protein is expressed in the pancreas, in smooth muscle cells of the kidney, lung, and gastrointestinal (GI) tract, and in myocytes of the heart [16]
In preclinical and in-vitro studies, this combination is being researched because the two peptides act through different endogenous receptor pathways
While the combination therapy CagriSema remains the stronger option for maximum weight loss, cagrilintide alone has clear potential as a treatment
Diabetes 55 , 21592170 (2006)
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